TAOS

A world-first in tissue repair, TAOS™ is a unique regenerative medicine technology platform that enhances tissue repair.

Optimal tissue healing requires a supportive environment that the body’s regenerative cells and repair factors can permeate and exert their effect.

TAOS® is an advanced tissue matrix which offers a number of important advances over current natural or interventional approaches to tissue healing, including:

  • TAOS® forms a 3-D porous structure which creates a template for tissue repair
  • It is an easy use, premade, injectable material that can be used in a range of hard and soft tissues
  • Regenerative agents can be delivered safely and cost effectively to the site of action eg local release of growth factors and/or cells
  • Safe and well tolerated biodegradable matrix formed of FDA approved components

TAOS® is thermo-setting, exploiting the process of “liquid sintering”; a unique and patented mechanism which converts an injectable paste into a porous solid minutes after entering the body. 

This proprietary approach is designed to be entirely biocompatible and replaces the damaging setting mechanisms (e.g. heat-generating, UV or chemically-induced curing) that limit the use of current products used in tissue repair applications.

 

The ability to inject the material removes the need for invasive surgery, meaning that operation and rehabilitation times and post-operative complications are all reduced. The material then degrades naturally, leaving behind only newly formed tissue within the patient.

 

The scope of potential products enabled by the TAOS® technology is large; spanning hard and soft tissue applications, and allows for the localised delivery of small molecules, biologicals and cell therapies at the intended site of action.

 

Locate is developing a number of novel products using TAOS, initially targeted at orthopaedic applications but we are also is exploring regenerative medicine opportunities in other tissue types.